Rosenbaum Robert A, Benyo Jeffrey S, O'Connor Robert E, Passarello Brent A, Williams Daniel R, Humphrey Brian D, Ross Robert W, Berry James M, Krebs Jeffrey G
Department of Emergency Medicine, Christiana Care Health System, Newark, DE 19718, USA.
Ann Emerg Med. 2004 Dec;44(6):628-34. doi: 10.1016/j.annemergmed.2004.03.012.
Patients with communicable diseases may require respiratory isolation to reduce the chance of transmission to health care workers and the public. This project was conducted to determine whether negative-pressure isolation for multiple patients can be achieved quickly and effectively using general hospital space not previously dedicated to respiratory isolation.
The physical therapy gymnasium was the area designated to test the ability to create a negative-pressure isolation environment in a large space. The conversion was planned in advance of an unscheduled drill to convert the space. Four high-efficiency particulate air (HEPA) filtered forced air machines were used to generate negative pressure. The units were vented to the outside air by a 25-foot length of 10-inch-diameter reusable duct. We evaluated the time needed for equipment setup and room conversion and noted any subjective difficulty with either setup or operation of the equipment. We measured the ability of the equipment to generate a negative air pressure relative to adjacent areas and determined the noise levels created during the use of different combinations of machines at various power settings.
After drill activation and the request for equipment setup, 1 hour was required to convert the physical therapy gymnasium into an operational negative-pressure environment. The room pressure readings "high" power ranged from -1.5 to -13 Pa (-0.006 to -0.052 inches of water), and noise levels ranged from 70 to 76 dB. Calculated air changes per hour using 1, 2, 3, or 4 units running simultaneously at "high" power were 4.1, 8.2, 12.3, and 16.4, respectively. Using 4 units at once running at "low" power setting yielded 8.2 air changes per hour and generated a room pressure reading of -8.0 Pa, or -0.032 inches of water.
Portable HEPA filtered forced air units are an effective means of creating large patient care areas with the negative-pressure environment required for respiratory isolation. This design results in a significantly lower-cost alternative compared with construction of individual rooms or units with similar capability and can be retrofitted to existing space. This type of unit would allow treatment of many more patients than current hospital capability would permit and would be an important asset in meeting the needs created by bioterrorism or a naturally occurring epidemic.
传染病患者可能需要呼吸道隔离,以降低传染给医护人员和公众的几率。开展本项目是为了确定利用此前未专门用于呼吸道隔离的综合医院空间,能否快速、有效地实现对多名患者的负压隔离。
物理治疗健身房是指定用于测试在大空间内营造负压隔离环境能力的区域。在一次临时演练之前就规划好了空间转换。使用四台高效空气过滤器(HEPA)过滤的强制空气机器来产生负压。这些设备通过一根25英尺长、直径10英寸的可重复使用管道排到室外空气中。我们评估了设备设置和房间转换所需的时间,并记录了设备设置或操作过程中存在的任何主观困难。我们测量了设备相对于相邻区域产生负压的能力,并确定了在不同功率设置下使用不同组合机器时产生的噪音水平。
演练启动并要求设置设备后,需要1小时将物理治疗健身房转换为可运行的负压环境。房间压力读数在“高”功率下为-1.5至-13帕斯卡(-0.006至-0.052英寸水柱),噪音水平为70至76分贝。使用1、2、3或4台设备同时在“高”功率下运行时,每小时的换气次数分别为4.1、8.2、12.3和16.4次。一次使用4台设备在“低”功率设置下运行,每小时换气次数为8.2次,房间压力读数为-8.0帕斯卡,即-0.032英寸水柱。
便携式HEPA过滤强制空气设备是创建具有呼吸道隔离所需负压环境的大型患者护理区域的有效手段。与建造具有类似功能的单独房间或单元相比,这种设计成本显著更低,并且可以对现有空间进行改造。这种类型的设备能够治疗的患者数量将远超当前医院的能力,并且将成为满足生物恐怖主义或自然发生的流行病所产生需求的一项重要资产。