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Human endogenous retroviruses in health and disease: a symbiotic perspective.

作者信息

Ryan Frank P

机构信息

Southwest Primary Care Trust, Fulwood House, 5 Old Fulwood Road, Sheffield, S10 3TH, UK.

出版信息

J R Soc Med. 2004 Dec;97(12):560-5. doi: 10.1177/014107680409701202.

Abstract
摘要

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The role of human endogenous retroviruses in trophoblast differentiation and placental development.
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Human endogenous retroviruses: transposable elements with potential?
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Retroelements and the human genome: new perspectives on an old relation.
Proc Natl Acad Sci U S A. 2004 Oct 5;101 Suppl 2(Suppl 2):14572-9. doi: 10.1073/pnas.0404838101. Epub 2004 Aug 13.
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Evidence of selection on the domesticated ERVWE1 env retroviral element involved in placentation.
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The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.
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The endogenous retroviral locus ERVWE1 is a bona fide gene involved in hominoid placental physiology.
Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1731-6. doi: 10.1073/pnas.0305763101. Epub 2004 Feb 2.
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Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.
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An endogenous retroviral long terminal repeat is the dominant promoter for human beta1,3-galactosyltransferase 5 in the colon.
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