Su Shu-lan, Wu Qi-nan, Ouyang Zhen, Wu De-kang, Chen Jun
Department of Pharmaceutical Engineering of Jiangsu University, Zhenjian 212013 China.
Zhongguo Zhong Yao Za Zhi. 2004 Sep;29(9):857-60.
To optimize the conditions of supercritical fluid extraction (SFE) for curcumin in Curcuma longa.
Optimum extraction conditions were studied by orthogonal tests. The extracts were analyzed by HPLC.
The optimal extraction conditions were pressure 25 MPa, temperature 55 degrees C, static time 4 h, dynamic time 5 h, flow rate of CO2 3.5 L x min(-1), co-solvent ethanol 30% (mL x g(-1)).
It is feasible to extract curcumin by SFE.
优化超临界流体萃取（SFE）姜黄中姜黄素的条件。
通过正交试验研究最佳萃取条件。提取物采用高效液相色谱法（HPLC）分析。
最佳萃取条件为压力25兆帕、温度55摄氏度、静态时间4小时、动态时间5小时、二氧化碳流速3.5升×分钟⁻¹、共溶剂乙醇30%（毫升×克⁻¹）。
采用超临界流体萃取法提取姜黄素是可行的。
