植物基因组中转座子的沉默：趁它们失势时加以抑制。
Silencing of transposons in plant genomes: kick them when they're down.
作者信息
Zilberman Daniel, Henikoff Steven
机构信息
Howard Hughes Medical Institute, Basic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.
出版信息
Genome Biol. 2004;5(12):249. doi: 10.1186/gb-2004-5-12-249. Epub 2004 Nov 16.
Abstract
Recent progress in understanding the silencing of transposable elements in the model plant Arabidopsis has revealed an interplay between DNA methylation, histone methylation and small interfering RNAs. DNA and histone methylation are not always sufficient to maintain silencing, and RNA-based reinforcement can be needed to maintain as well as initiate it.
摘要
在理解模式植物拟南芥中转座元件沉默方面的最新进展揭示了DNA甲基化、组蛋白甲基化和小干扰RNA之间的相互作用。DNA和组蛋白甲基化并不总是足以维持沉默，可能需要基于RNA的强化来维持和启动沉默。
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