变形链球菌的F-ATP酶操纵子启动子可根据外部pH值进行转录调控。
The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH.
作者信息
Kuhnert Wendi L, Zheng Guolu, Faustoferri Roberta C, Quivey Robert G
机构信息
Center for Oral Biology, Box 611, 601 Elmwood Ave., Rochester, NY 14642, USA.
出版信息
J Bacteriol. 2004 Dec;186(24):8524-8. doi: 10.1128/JB.186.24.8524-8528.2004.
Abstract
Streptococcus mutans F-ATPase, the major component of the acid-adaptive response of the organism, is transcriptionally upregulated at low pH. Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons.
摘要
变形链球菌F-ATP酶是该生物体酸适应性反应的主要成分，在低pH值下转录上调。F-ATP酶启动子与氯霉素乙酰转移酶的融合表明，使用含有链球菌ATP酶操纵子之间保守结构域的短启动子仍可观察到pH依赖性表达。
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