Vardi P, Markiewicz W, Levy J, Adler O, Riss E, Benderley A
Pediatrics. 1979 May;63(5):782-7.
Patients with acute glomerulonephritis often are seen with signs suggesting heart failure. Whether these signs are due to fluid overload secondary to kidney damage only, or whether there is associated myocardial damage has not been elucidated. Fourteen children with acute glomerulonephritis were studied by echocardiography during the edematous phase of the disease and five months later to evaluate cardiac function in this disease. Left ventricular size and function remained normal in all children throughout the study. The most consistent finding was enlargement of the left atrium during the edematous phase with a return toward normal values five months later. There was no correlation between blood pressure and the echocardiographic findings. This study suggests that signs of heart failure in acute glomerulonephritis are not due to myocardial damage but probably reflect fluid overload.
急性肾小球肾炎患者常出现提示心力衰竭的体征。这些体征是仅由于肾脏损害继发的液体超负荷所致，还是存在相关的心肌损害，目前尚未阐明。对14例急性肾小球肾炎患儿在疾病水肿期及5个月后进行超声心动图检查，以评估该疾病的心脏功能。在整个研究过程中，所有患儿的左心室大小和功能均保持正常。最一致的发现是水肿期左心房增大，5个月后恢复至正常值。血压与超声心动图检查结果之间无相关性。这项研究表明，急性肾小球肾炎中心力衰竭的体征并非由心肌损害引起，而可能反映了液体超负荷。
