Chandler Melanie J, Lacritz Laura H, Cicerello Antionette R, Chapman Sandra B, Honig Lawrence S, Weiner Myron F, Cullum C Munro
The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8846, USA.
J Clin Exp Neuropsychol. 2004 Nov;26(8):1128-33. doi: 10.1080/13803390490515540.
Three-word recall tasks are widely used as brief measures of verbal memory function, although interpretation of performance is complicated by variations in test instructions and procedures. The purpose of this study was to examine 3-word recall performance in samples of healthy subjects aged 5275 (M age = 70) and age 7692 (M age = 82) compared to patients with Alzheimer's Disease (AD) when explicit prompts to remember the words were given. Those in the younger aging group remembered significantly more words than those in the older sample after a brief delay (M= 2.8 and 2.3, respectively). However, the majority of control subjects recalled 2 or 3 words after the delay, with only 3% of the 5075 year old group and 17% of the 76+ year old group recalling 0 or 1 word on delayed recall. This is in stark contrast to the 87% of individuals with AD who recalled 0 or 1 word. Even though 3-word recall performance decreases with age, good recall (2 or 3 words) can be expected in most cases of normal aging.
尽管测试指令和程序的差异会使对测试结果的解释变得复杂,但三字回忆任务仍被广泛用作言语记忆功能的简要测量方法。本研究的目的是,在给予明确的单词记忆提示时,考察年龄在52至75岁(平均年龄 = 70岁)和76至92岁(平均年龄 = 82岁)的健康受试者样本与阿尔茨海默病(AD)患者相比的三字回忆表现。在短暂延迟后,年轻老年组的受试者记住的单词明显多于年长样本组的受试者(分别为平均2.8个和2.3个)。然而,大多数对照组受试者在延迟后回忆起2个或3个单词,50至75岁组中只有3%的受试者以及76岁及以上组中17%的受试者在延迟回忆时回忆起0个或1个单词。这与87%的AD患者回忆起0个或1个单词形成了鲜明对比。尽管三字回忆表现会随着年龄增长而下降,但在大多数正常衰老的情况下,仍可预期有良好的回忆表现(2个或3个单词)。