悉尼帕金森病的患病率。

Prevalence of Parkinson's disease in Sydney.

作者信息

Chan D K Y, Cordato D, Karr M, Ong B, Lei H, Liu J, Hung W T

机构信息

Department of Aged Care and Rehabilitation, Bankstown-Lidcombe Hospital, Bankstown, NSW, Australia.

出版信息

Acta Neurol Scand. 2005 Jan;111(1):7-11. doi: 10.1111/j.1600-0404.2004.00348.x.

DOI:10.1111/j.1600-0404.2004.00348.x

PMID:15595932

Abstract

OBJECTIVE

To examine the prevalence of Parkinson's disease (PD) in Bankstown, Sydney, using the same methodology as a previous study in Randwick, Sydney, Australia (1998-1999).

PARTICIPANTS AND METHODS

Twenty census districts (CDs) for the Bankstown local government area were randomly selected. Research personnel door-knocked every household within the CDs to locate people aged > or =55 years. A structured questionnaire (containing four screening questions for PD) was administered to those agreeing to participate. Screened positive participants were invited to come for a clinical examination. This is a continuation of the previous study and data have been combined.

RESULTS

Combining data for Bankstown and Randwick gave 1028 participants; crude prevalence, 780 per 100,000 (CI: 546-1077). In Bankstown, there were 501 participants aged > or =55 years (response rate 70%); 135 were screened positive with 101 (74.8%) agreeing to a clinical examination. The prevalence of PD in the Bankstown community was 3.4% (17 of 501) (95% CI: 1.98-5.43) for those aged > or =55 years; crude prevalence 776 per 100,000 (CI: 452-1241).

CONCLUSION

The combined results of two Sydney studies appear to indicate that Sydney has one of the highest prevalence estimates of PD in developed countries.

摘要

目的

采用与澳大利亚悉尼兰德威克先前一项研究（1998 - 1999年）相同的方法，调查悉尼班克斯敦帕金森病（PD）的患病率。

参与者与方法

随机选取班克斯敦地方政府区域的20个普查区（CD）。研究人员逐户走访这些普查区内年龄大于或等于55岁的居民。对同意参与的居民发放一份结构化问卷（包含四个帕金森病筛查问题）。筛查呈阳性的参与者被邀请前来进行临床检查。这是先前研究的延续，数据已合并。

结果

将班克斯敦和兰德威克的数据合并后有1028名参与者；粗患病率为每10万人780例（95%置信区间：546 - 1077）。在班克斯敦，有501名年龄大于或等于55岁的参与者（应答率70%）；135人筛查呈阳性，其中101人（74.8%）同意进行临床检查。在班克斯敦社区，年龄大于或等于55岁人群中帕金森病的患病率为3.4%（501人中17例）（95%置信区间：1.98 - 5.43）；粗患病率为每10万人776例（95%置信区间：452 - 1241）。