Chang Yo-Chen, Chang Cheng-Hsien, Liu Yi-Tseng, Tsai Kun-Bow, Liu Ta-Chih, Lin Yun-Nan
Department of Ophthalmology, Kaohsiung, Taiwan.
Ophthalmic Plast Reconstr Surg. 2004 Nov;20(6):461-3. doi: 10.1097/01.iop.0000144791.05993.64.
Spontaneous and complete regression of malignant neoplasms is extremely unusual. To our knowledge, this case report is the first description of spontaneous regression of an extranodal malignant lymphoma occurring in the conjunctiva and orbit. A 40-year-old woman noticed a pink conjunctival mass at the medial aspect of her left eye that had been present for 3 weeks. She presented on May 5, 2003. Ophthalmologic examination showed a salmon-colored mass along the lateral side of the caruncle. CT revealed a mass in the medial orbit. Surgical biopsy exhibited a malignant lymphoma, diffuse large B-cell type. After biopsy, the tumor spontaneously decreased in size and completely disappeared in 5 weeks. At 6 months' follow-up, the tumor had not recurred.
恶性肿瘤的自发完全消退极为罕见。据我们所知，本病例报告是关于结膜和眼眶发生的结外恶性淋巴瘤自发消退的首次描述。一名40岁女性注意到左眼内侧出现粉红色结膜肿物，已持续3周。她于2003年5月5日就诊。眼科检查显示在泪阜外侧有一个鲑鱼色肿物。CT显示眼眶内侧有一个肿物。手术活检显示为弥漫性大B细胞型恶性淋巴瘤。活检后，肿瘤大小自发减小，并在5周内完全消失。在6个月的随访中，肿瘤未复发。
