G9 型轮状病毒成为台湾南部感染性肠胃炎的主要病因

Emergence of G9 serotype rotavirus as a major cause of infectious gastroenteritis in southern Taiwan.

作者信息

Sung Yuk-Lan, Huang Yun-Feng, Huang Chun-Fong, Chen Kow-Tong, Chen Hour-Young, Lee Guan-Hsien, Nong Bao-Ren, Lin Chun-Sheng, Chuang Chin-Ming, Liu Feng-Chuan, Chen Chi-Shan, Lin Chun-Chin, Hsieh Kai-Sheng, Liu Yung-Ching

机构信息

Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

出版信息

J Microbiol Immunol Infect. 2004 Dec;37(6):322-6.

PMID:15599463

Abstract

Infectious gastroenteritis is a common illness in children. This study investigated the etiology and clinical manifestations of hospitalized children with symptoms of infectious gastroenteritis in southern Taiwan. We studied 467 consecutive patients with infectious gastroenteritis aged from 2 days to 10 years hospitalized from April 2001 to March 2002. Rotavirus was the most common etiology (57%) of infectious gastroenteritis in these patients. Bacterial infection was noted in 57 cases (12%). Rotavirus was found in 92% of nosocomial infectious gastroenteritis (p < or = 0.001). Bloody stool was a presentation of bacterial infection in 74% of cases and rotavirus gastroenteritis in 8% of cases (p < or = 0.001). The G serotype of rotavirus was identified in 87 patients. Serotype G1 was the most common (51%), followed by G9 (31%). The emergence of serotype G9 strains in rotavirus infection has not been previously reported from Taiwan. Incorporation of G9 rotavirus into vaccines should be considered.

摘要

感染性肠胃炎是儿童常见疾病。本研究调查了台湾南部有感染性肠胃炎症状的住院儿童的病因及临床表现。我们研究了2001年4月至2002年3月期间连续住院的467例年龄从2天至10岁的感染性肠胃炎患儿。轮状病毒是这些患儿感染性肠胃炎最常见的病因（57%）。57例（12%）发现有细菌感染。在92%的医院感染性肠胃炎病例中发现了轮状病毒（p≤0.001）。74%的细菌感染病例和8%的轮状病毒肠胃炎病例出现血便（p≤0.001）。对87例患者的轮状病毒G血清型进行了鉴定。G1血清型最为常见（51%），其次是G9（31%）。台湾此前尚未报道过轮状病毒感染中G9血清型毒株的出现。应考虑将G9轮状病毒纳入疫苗。