Mustian Karen M, Katula Jeffrey A, Gill Diane L, Roscoe Joseph A, Lang David, Murphy Karen
Behavioral Medicine Unit, Department of Radiation Oncology, James P. Wilmot Cancer Center, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 704, Rochester, NY 14642, USA.
Support Care Cancer. 2004 Dec;12(12):871-6. doi: 10.1007/s00520-004-0682-6. Epub 2004 Sep 30.
Health-related quality of life (HRQL) and self-esteem are often diminished among women diagnosed and treated for breast cancer. Tai Chi is a moderate form of exercise that may be an effective therapy for improving HRQL and self-esteem among these women. We sought to compare the efficacy of Tai Chi Chuan (TCC) and psychosocial support (PST) for improving HRQL and self-esteem among breast cancer survivors.
A group of 21 women diagnosed with breast cancer, who had completed treatment within the last 30 months were randomized to receive 12 weeks of TCC or PST. Participants in both groups met three times a week for 60 minutes. HRQL and self-esteem were assessed at baseline, 6 weeks, and 12 weeks.
The TCC group demonstrated significant improvements in HRQL, while the PST group reported declines in HRQL, with the differences between the two groups approaching significance at week 12. Additionally, the TCC group exhibited improvements in self-esteem, while the PST group reported declines in self-esteem, with the differences between groups reaching statistical significance at week 12. These findings, coupled with a visual inspection of the raw change scores, support the plausibility of a dose-response relationship concerning Tai Chi.
In this pilot investigation, the TCC group exhibited improvements in HRQL and self-esteem from baseline to 6 and 12 weeks, while the support group exhibited declines. Randomized, controlled clinical trials with larger sample sizes are needed.
在被诊断患有乳腺癌并接受治疗的女性中,与健康相关的生活质量(HRQL)和自尊往往会降低。太极拳是一种适度的运动形式,可能是改善这些女性HRQL和自尊的有效疗法。我们试图比较太极拳(TCC)和心理社会支持(PST)对提高乳腺癌幸存者HRQL和自尊的疗效。
一组21名被诊断患有乳腺癌且在过去30个月内完成治疗的女性被随机分为接受12周的TCC或PST。两组参与者每周会面三次,每次60分钟。在基线、6周和12周时评估HRQL和自尊。
TCC组的HRQL有显著改善,而PST组报告HRQL下降,两组之间的差异在第12周接近显著水平。此外,TCC组的自尊有所改善,而PST组报告自尊下降,两组之间的差异在第12周达到统计学显著水平。这些发现,再加上对原始变化分数的直观检查,支持了太极拳剂量反应关系的合理性。
在这项初步调查中,TCC组从基线到6周和12周时HRQL和自尊有所改善,而支持组则出现下降。需要进行更大样本量的随机对照临床试验。