University of Utah, Salt Lake City, UT, USA.
Integr Cancer Ther. 2013 Nov;12(6):464-74. doi: 10.1177/1534735413485418. Epub 2013 Apr 25.
The purpose of this randomized controlled trial (RCT) was to examine the feasibility and acceptability of a Tai Chi Chih (TCC) intervention in senior female cancer survivors with physical functioning limitations, and its effects on health-related quality of life (QOL).
This was a two-armed, parallel group, RCT with 12-weeks of Tai Chi Chih or Health Education Control.
Sixty-three senior (M age = 67 years, SD = 7.15) female cancer survivors (83% breast cancer, stages I-III) with physical functioning limitations (SF-12 Health Survey role-physical & physical functioning subscales) were randomized to 12-weeks of TCC or Health Education control (HEC). Primary outcomes were feasibility and acceptability. Secondary outcomes included health-related QOL (SF-36 Health Survey), and participants' qualitative feedback on the intervention.
Retention (TCC = 91%; HEC = 81%) and class attendance (TCC = 79%; HEC = 83%) rates, and satisfaction levels for both study arms were high, but did not significantly differ from one another. At one-week post-intervention, none of the SF-36 scores differed between the TCC and HEC groups. Within-group analyses revealed significant improvements in the mental component summary score in TCC (p = 0.01), but not in HEC. Qualitative analyses indicated that the TCC group felt they received mental and physical benefits, whereas HEC group reported on social support benefits and information received.
The TCC intervention was found to be a feasible and acceptable modality for senior female cancer survivors. Future, larger definitive trials are needed to clarify TCC dosage effects on QOL in this vulnerable population.
本随机对照试验（RCT）的目的是检验太极拳气功（TCC）干预对身体功能受限的老年女性癌症幸存者的可行性和可接受性，及其对健康相关生活质量（QOL）的影响。
这是一项为期 12 周的 TCC 或健康教育对照的双臂、平行组 RCT。
63 名（M 年龄=67 岁，SD=7.15）身体功能受限（SF-12 健康调查角色身体和身体功能子量表）的老年（M 年龄=67 岁，SD=7.15）女性癌症幸存者（83%乳腺癌，I-III 期）被随机分为 12 周的 TCC 或健康教育对照（HEC）。主要结局是可行性和可接受性。次要结局包括健康相关 QOL（SF-36 健康调查），以及参与者对干预措施的定性反馈。
保留率（TCC=91%；HEC=81%）和课堂出勤率（TCC=79%；HEC=83%）都很高，且两组的满意度也很高，但两组之间没有显著差异。在干预后一周，TCC 和 HEC 组的 SF-36 评分均无差异。组内分析显示 TCC 组的心理成分综合评分有显著提高（p=0.01），而 HEC 组则没有。定性分析表明，TCC 组认为他们获得了身心两方面的益处，而 HEC 组则报告了社会支持方面的益处和所获得的信息。
TCC 干预对老年女性癌症幸存者是一种可行和可接受的方式。未来需要更大规模的确定性试验来阐明 TCC 剂量对这一脆弱人群 QOL 的影响。
