Aapro Matti S, Molassiotis Alexander, Olver Ian
IMO Clinique de Genolier, CH-1272 Genolier, Switzerland.
Support Care Cancer. 2005 Feb;13(2):117-21. doi: 10.1007/s00520-004-0745-8. Epub 2004 Dec 15.
Anticipatory nausea and vomiting (ANV) is not only a learned response but can occur without prior exposure to chemotherapy depending on patient emotional distress and expectations. The best method to avoid development or reinforcement of ANV is to avoid both vomiting and nausea from the first exposure to chemotherapy. If ANV develops, benzodiazepines have been documented to help in adult patients, and several psychological techniques are also of help, including systematic desensitization. The evidence on which these conclusions are based is reviewed in this article.
预期性恶心和呕吐(ANV)不仅是一种习得性反应,而且根据患者的情绪困扰和预期,即使没有事先接触过化疗也可能发生。避免ANV发生或加重的最佳方法是从首次接触化疗开始就避免呕吐和恶心。如果发生了ANV,有文献记载苯二氮䓬类药物对成年患者有帮助,几种心理技术也有帮助,包括系统脱敏疗法。本文将对得出这些结论所依据的证据进行综述。