Kulkarni Rahul V, Huang Kerwyn Casey, Kloster Morten, Wingreen Ned S
NEC Laboratories America, Inc., Princeton, New Jersey 08540, USA.
Phys Rev Lett. 2004 Nov 26;93(22):228103. doi: 10.1103/PhysRevLett.93.228103. Epub 2004 Nov 23.
In E. coli, accurate cell division depends upon the oscillation of Min proteins from pole to pole. We provide a model for the polar localization of MinD based only on diffusion, a delay for nucleotide exchange, and different rates of attachment to the bare membrane and the occupied membrane. We derive analytically the probability density, and correspondingly the length scale, for MinD attachment zones. Our simple analytical model illustrates the processes giving rise to the observed localization of cellular MinD zones.
在大肠杆菌中，精确的细胞分裂依赖于Min蛋白在两极之间的振荡。我们仅基于扩散、核苷酸交换延迟以及与裸露膜和被占据膜的不同附着速率，提供了一个MinD极性定位的模型。我们通过分析得出了MinD附着区域的概率密度以及相应的长度尺度。我们简单的分析模型阐释了导致观察到的细胞MinD区域定位的过程。
