Schmidt B J, Piva S, Schalch A L, Ortega C, Sousa M M, Torres D B, Krynski S
Arq Neuropsiquiatr. 1978 Dec;36(4):312-5. doi: 10.1590/s0004-282x1978000400003.
The presence of antithyroid antibodies (antithyroglobulin and antimicrosomal) in serum of patients with Down's syndrome and their respective mothers were studied based on data from the literature, showing a possible correlation between the presence of these antibodies in the serum of mothers and the birth of mongoloid children. Antithyroid antibodies were studied in 40 patients with Down's syndrome, with ages ranging from 5 months to 21 years old, 24 males and 16 females and in the respective mothers whose ages varied from 22 to 66 years. In none of the analyzed sera of the mongoloids as well of their mothers, the authors were able to detect the antithyroid antibodies studied.
根据文献数据，对唐氏综合征患者及其母亲血清中抗甲状腺抗体（抗甲状腺球蛋白和抗微粒体）的存在情况进行了研究，结果显示母亲血清中这些抗体的存在与先天愚型儿童的出生之间可能存在关联。对40例年龄在5个月至21岁之间的唐氏综合征患者（24例男性，16例女性）及其年龄在22岁至66岁之间的母亲进行了抗甲状腺抗体研究。在对这些先天愚型患者及其母亲的血清分析中，作者均未检测到所研究的抗甲状腺抗体。
