Altman E S, Rea M M, Mintz J, Miklowitz D J, Goldstein M J, Hwang S
Department of Psychology, University of California, Los Angeles 90024-1563.
Psychiatry Res. 1992 Jan;41(1):1-8. doi: 10.1016/0165-1781(92)90012-r.
Prospectively collected data on 19 recently hospitalized patients with bipolar disorder were examined for prodromal changes preceding relapse. The 4-month periods before six manic and six depressive relapses were compared with each other and with a comparable period for seven patients who did not relapse. The Brief Psychiatric Rating Scale was used to assess symptoms. Significant elevations in unusual thought content were found 1 month before manic relapse. Depressive relapsers evidenced higher levels of conceptual disorganization throughout the prerelapse period. Nonrelapsers showed very stable symptom profiles.
对前瞻性收集的19例近期住院的双相情感障碍患者的数据进行检查，以了解复发前的前驱变化。将6次躁狂发作和6次抑郁发作前的4个月时间段相互比较，并与7例未复发患者的可比时间段进行比较。使用简明精神病评定量表评估症状。发现躁狂复发前1个月异常思维内容显著升高。抑郁复发者在复发前期整个阶段概念紊乱水平较高。未复发者症状表现非常稳定。
