Bell Steven L, Palsson Bernhard Ø
Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Bioinformatics. 2005 Apr 15;21(8):1739-40. doi: 10.1093/bioinformatics/bti228. Epub 2004 Dec 21.
The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.
The C-code, along with a Windows executable and sample network reaction files, are available at http://systemsbiology.ucsd.edu
极端途径集是生化反应网络中所有可能稳态通量图的生成集，可从反映网络拓扑结构的类似关联矩阵的化学计量矩阵计算得出。在此，我们描述一种用于计算这些途径的著名算法的实现，并总结现有软件的功能特点。
C代码以及Windows可执行文件和示例网络反应文件可在http://systemsbiology.ucsd.edu获取。
