计算机辅助生物化学反应网络分析（IBRENA）：一个用于反应网络模拟和分析的软件包。
In silico Biochemical Reaction Network Analysis (IBRENA): a package for simulation and analysis of reaction networks.
作者信息
Liu Gang, Neelamegham Sriram
机构信息
Department of Chemical and Biological Engineering, State University of New York, Buffalo, NY 14260, USA.
出版信息
Bioinformatics. 2008 Apr 15;24(8):1109-11. doi: 10.1093/bioinformatics/btn061. Epub 2008 Feb 28.
SUMMARY
We present In silico Biochemical Reaction Network Analysis (IBRENA), a software package which facilitates multiple functions including cellular reaction network simulation and sensitivity analysis (both forward and adjoint methods), coupled with principal component analysis, singular-value decomposition and model reduction. The software features a graphical user interface that aids simulation and plotting of in silico results. While the primary focus is to aid formulation, testing and reduction of theoretical biochemical reaction networks, the program can also be used for analysis of high-throughput genomic and proteomic data.
AVAILABILITY
The software package, manual and examples are available at http://www.eng.buffalo.edu/~neel/ibrena
摘要
我们展示了计算机生化反应网络分析（IBRENA），这是一个软件包，它具备多种功能，包括细胞反应网络模拟和灵敏度分析（正向和伴随方法），还结合了主成分分析、奇异值分解和模型简化。该软件具有图形用户界面，有助于对计算机模拟结果进行模拟和绘图。虽然主要重点是辅助理论生化反应网络的构建、测试和简化，但该程序也可用于高通量基因组和蛋白质组数据的分析。
可用性
软件包、手册和示例可在http://www.eng.buffalo.edu/~neel/ibrena获取。
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