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8 周龄雄性法国斗牛犬存在先天性肝憩室遗留的纤毛前肠,导致脐胆管窦道形成,且胆囊缺如。

Patent hepatic ciliated foregut remnant resulting in an umbilicobiliary sinus tract, with gallbladder agenesis, in an 8-wk-old male French Bulldog.

机构信息

Dick White Referrals, Six Mile Bottom, Cambridgeshire, UK.

College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.

出版信息

J Vet Diagn Invest. 2023 Mar;35(2):196-200. doi: 10.1177/10406387221147317. Epub 2023 Jan 4.

Abstract

Hepatic ciliated foregut remnants or cysts are congenital abnormalities resulting from retention of embryonic ciliated foregut within the liver. These structures are rarely reported in the human medical literature and have not been reported in the veterinary literature previously, to our knowledge. We describe here a case of an 8-wk-old male French Bulldog with a congenital patent hepatic ciliated foregut remnant resulting in an umbilicobiliary sinus tract. The dog also had concurrent gallbladder agenesis. The patient had yellow fluid discharging from the umbilicus, mimicking a patent urachus. Surgical exploration, removal, and histology provided a conclusive diagnosis of a hepatic foregut remnant and therapeutic resolution of the clinical signs. The histologic appearance of a hepatic foregut remnant is classical, namely a duct composed of 4 layers: an inner ciliated epithelial lining, loose connective tissue, smooth muscle, and a fibrous capsule.

摘要

肝的纤毛前肠残余物或囊肿是先天性异常,是由于胚胎纤毛前肠在肝脏内滞留引起的。据我们所知,这些结构在人类医学文献中很少报道,在兽医文献中也没有报道过。我们在这里描述了一例 8 周大的雄性法国斗牛犬,患有先天性开放的肝纤毛前肠残余物,导致脐胆瘘管。该犬还伴有胆囊发育不全。患犬从脐部排出黄色液体,类似于开放的脐尿管。手术探查、切除和组织学检查提供了一个明确的肝前肠残余物的诊断,并治愈了临床症状。肝前肠残余物的组织学表现是经典的,即由 4 层组成的导管:内层纤毛上皮衬里、疏松结缔组织、平滑肌和纤维囊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c0/9999390/65805d480a01/10.1177_10406387221147317-fig1.jpg

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