Otani F, Ejiri K, Kanemori H, Kudo T, Sekiba K
Department of Obstetrics and Gynecology, Okayama University Medical School, Japan.
Acta Med Okayama. 1992 Feb;46(1):17-22. doi: 10.18926/AMO/32681.
The taurine concentration and uptake in platelets obtained from normal pregnant women and gestosis patients with edema, proteinuria and hypertension (EPH gestosis) were investigated. The taurine concentration in platelets showed a marked increase in severe EPH gestosis compared with normal pregnancy or mild and moderate EPH gestosis, while the plasma taurine concentration did not change significantly. Taurine uptake in platelets paralleled the severity of EPH gestosis. The Vmax of the uptake in severe EPH gestosis was about 2.4 times higher than that in normal pregnancy or mild and moderate EPH gestosis, but no significant difference was seen in the Km value among these groups.
对正常孕妇以及患有水肿、蛋白尿和高血压（妊娠高血压综合征）的妊娠中毒症患者的血小板中的牛磺酸浓度和摄取情况进行了研究。与正常妊娠或轻度及中度妊娠高血压综合征相比，重度妊娠高血压综合征患者血小板中的牛磺酸浓度显著升高，而血浆牛磺酸浓度无明显变化。血小板中的牛磺酸摄取情况与妊娠高血压综合征的严重程度平行。重度妊娠高血压综合征患者摄取的最大反应速度（Vmax）比正常妊娠或轻度及中度妊娠高血压综合征患者高约2.4倍，但这些组之间的米氏常数（Km值）没有显著差异。
