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欧洲腭裂研究:唇腭裂患者治疗效果的多中心研究。第5部分:讨论与结论。

The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. Part 5: discussion and conclusions.

作者信息

Shaw William C, Brattström Viveca, Mølsted Kirsten, Prahl-Andersen Birte, Roberts Christopher T, Semb Gunvor

机构信息

Department for Oral Health and Development, University Dental Hospital of Manchester, Manchester, United Kingdom.

出版信息

Cleft Palate Craniofac J. 2005 Jan;42(1):93-8. doi: 10.1597/02-119.5.1.

Abstract

OBJECTIVE

To review the lessons learned from a longitudinal intercenter comparison study.

DESIGN

Longitudinal cohort study.

SETTING

Multidisciplinary cleft services in Northern Europe.

SUBJECTS

Individuals with repaired complete unilateral cleft lip and palate.

MAIN OUTCOMES MEASURES

The first four papers in this series report amount of treatment, cephalometric form, nasolabial appearance, dental arch relationship, patient/parent satisfaction. This paper considers the consistency of outcome at the five centers over time, and other relationships between outcomes.

RESULTS

Some outcomes measured in childhood can be predictive over time. The amount of treatment does not correlate with the quality of clinical outcome.

CONCLUSIONS

Measurement of clinical outcome in childhood is an important and valid form of clinical audit. Intercenter studies are more informative than single center reports, and will have an important future role in cleft care.

摘要

目的

回顾一项纵向多中心比较研究的经验教训。

设计

纵向队列研究。

地点

北欧的多学科腭裂治疗服务机构。

研究对象

单侧完全性唇腭裂修复患者。

主要观察指标

本系列的前四篇论文报告了治疗量、头影测量形态、鼻唇外观、牙弓关系、患者/家长满意度。本文考虑了五个中心随时间推移的结果一致性,以及结果之间的其他关系。

结果

儿童期测量的一些结果随时间推移具有预测性。治疗量与临床结果质量无关。

结论

儿童期临床结果的测量是临床审计的一种重要且有效的形式。多中心研究比单中心报告提供的信息更多,并且在腭裂治疗的未来中将发挥重要作用。

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