洗必泰预防牙槽骨炎：一项荟萃分析综述
Prevention of alveolar osteitis with chlorhexidine: a meta-analytic review.
作者信息
Caso Antonio, Hung Li-Kuei, Beirne O Ross
机构信息
University of Washington School of Dentistry, Department of Oral and Maxillofacial Surgery, Seattle, WA 98195-7134, USA.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Feb;99(2):155-9. doi: 10.1016/j.tripleo.2004.05.009.
OBJECTIVE
The objective of this study was to assess if chlorhexidine (CHX) rinse decreases the occurrence of alveolar osteitis (AO) following third molar removal.
STUDY DESIGN
A literature search identified 7 randomized prospective clinical trials reporting incidence of AO following removal of mandibular third molars. Studies were combined into 2 groups and summary relative risks were calculated for each group. One group of studies evaluated rinsing on the day of surgery only and the second group of studies rinsed at least on the day of surgery and several days after surgery.
RESULTS
The relative risk for the single rinse group was 1.36 (95% confidence interval [CI] 0.80, 2.33), P>.05, whereas for the multiple rinse group, the relative risk was 1.90 (95% CI 1.46, 2.47), P<.05.
CONCLUSION
Rinsing with CHX on the day of surgery and several days after may reduce the incidence of AO.
目的
本研究的目的是评估洗必泰（CHX）冲洗是否能降低拔除第三磨牙后牙槽骨炎（AO）的发生率。
研究设计
文献检索确定了7项随机前瞻性临床试验，报告了下颌第三磨牙拔除后AO的发生率。研究被分为2组，并计算了每组的汇总相对风险。一组研究仅评估了手术当天的冲洗情况，另一组研究至少在手术当天和术后几天进行了冲洗。
结果
单次冲洗组的相对风险为1.36（95%置信区间[CI]0.80，2.33），P>0.05，而多次冲洗组的相对风险为1.90（95%CI 1.46，2.47），P<0.05。
结论
手术当天及术后几天用CHX冲洗可能会降低AO的发生率。
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