Meirelles Rodrigo Luz, Aggio Fabio Bom, Costa Rogério Alves, Farah Michel Eid
Department of Ophthalmology, Instituto da Visão-IPEPO, Federal University of São Paulo, Rua Botucatu 822, São Paulo, SP 04023-900, Brazil.
Graefes Arch Clin Exp Ophthalmol. 2005 Jan;243(1):76-81. doi: 10.1007/s00417-004-0956-1. Epub 2004 Aug 4.
To report the STRATUS optical coherence tomography (STRATUSOCT) findings in a patient with unilateral coloboma-like excavation of the optic disc without pit but secondary retinoschisis, as well as to discuss the possible involved pathophysiologic mechanisms.
Observational case report. STRATUSOCT findings in a 66-year-old woman with a coloboma-like excavation of the optic disc without pit but secondary retinoschisis encompassing the macular region, along with evidence of a mild epiretinal membrane superonasal to the disc were evaluated.
STRATUSOCT showed signs of a connection between the perineural space and the inner retinal layers on the temporal optic disc border, as well as schisis-like changes extending from the disc to the macula, with cystoid degeneration and two lamellar holes in their nasal portion.
The use of third generation OCT afforded an enhanced visualization of retinal structures, revealing signs of fluid at several distinct levels, as well as deep and superficial inner breaks apart from the schisis cavity. We are unaware of such previous reports, and could find no reference to them in a computerized search using MEDLINE. In addition, our study supports a common pathomechanism for the development of macular complications in optic pits and colobomas.
报告1例无视盘凹陷但继发视网膜劈裂的单侧视盘缺损样凹陷患者的STRATUS光学相干断层扫描（STRATUS OCT）检查结果，并探讨可能涉及的病理生理机制。
观察性病例报告。评估1例66岁女性患者的STRATUS OCT检查结果，该患者视盘有缺损样凹陷但无视盘凹陷，继发视网膜劈裂累及黄斑区，同时有视盘鼻上方轻度视网膜前膜的证据。
STRATUS OCT显示颞侧视盘边缘神经周围间隙与视网膜内层之间存在连接迹象，以及从视盘延伸至黄斑的劈裂样改变，其鼻侧部分有囊样变性和两个板层裂孔。
第三代光学相干断层扫描（OCT）能更好地显示视网膜结构，揭示多个不同层面的液体迹象，以及除劈裂腔外的深层和浅层视网膜内层裂孔。我们未发现此前有此类报告，在使用MEDLINE进行的计算机检索中也未找到相关参考文献。此外，我们的研究支持视盘凹陷和视盘缺损黄斑并发症发生的共同病理机制。
