动物铁蛋白和细菌铁蛋白含有醌类物质。

Animal ferritin and bacterioferritin contain quinones.

作者信息

al-Massad F K, Kadir F H, Moore G R

机构信息

Centre for Metalloprotein Spectroscopy and Biology, School of Chemical Sciences, University of East Anglia, Norwich, U.K.

出版信息

Biochem J. 1992 Apr 1;283 ( Pt 1)(Pt 1):177-80. doi: 10.1042/bj2830177.

DOI:10.1042/bj2830177

PMID:1567365

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1131011/

Abstract

The origin of the 440 nm fluorescence of horse spleen ferritin and of Pseudomonas aeruginosa and Azotobacter vinelandii bacterioferritin has been investigated using a Nitro Blue Tetrazolium/glycinate colorimetric test specific for quiones [Paz, Flückiger, Boak, Kagan & Gallop (1991) J. Biol. Chem. 266, 689-692]. The results of the analysis indicate that ferritin and bacterioferritins contain quinones. A possible functional role of these quinones in iron uptake and release is described, as is the possibility that the presence of quinones in these proteins results from oxidative damage.

摘要

利用对醌类物质具有特异性的硝基蓝四唑/甘氨酸比色法[帕斯、弗吕基格、博克、卡根和加洛普（1991年）《生物化学杂志》266卷，689 - 692页]，研究了马脾铁蛋白、铜绿假单胞菌和棕色固氮菌细菌铁蛋白440纳米荧光的起源。分析结果表明，铁蛋白和细菌铁蛋白含有醌类物质。描述了这些醌类物质在铁摄取和释放中可能的功能作用，以及这些蛋白质中醌类物质的存在可能是由氧化损伤导致的可能性。