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旅行相关非伤寒沙门氏菌病:地理和季节差异及血清型分布

Travel-associated non-typhoidal salmonellosis: geographical and seasonal differences and serotype distribution.

作者信息

Ekdahl K, de Jong B, Wollin R, Andersson Y

机构信息

Department of Epidemiology, Swedish Institute for Infectious Disease Control (SMI), Solna, Sweden.

出版信息

Clin Microbiol Infect. 2005 Feb;11(2):138-44. doi: 10.1111/j.1469-0691.2004.01045.x.

DOI:10.1111/j.1469-0691.2004.01045.x
PMID:15679488
Abstract

The Swedish database on notifiable communicable diseases was used to identify 24 803 cases of travel-associated non-typhoidal salmonellosis from the period 1997-2003. Serotype data were available for 24 358 (98.2%) of these cases, which were compared with a data set from the same period of 16 255 randomly selected Swedish residents with a history of recent overnight travel outside Sweden. The highest risk of disease was seen in travellers returning from East Africa (471/100 000 travellers; 95% CI 294-755), or the Indian subcontinent (474/100 000; 95% CI 330-681). Children aged 0-6 years were at higher risk than travellers of other ages (OR 2.4; 95% CI 2.1-2.8). Some distinct seasonal patterns could be distinguished, with highest (adjusted) risk in December in East Asia, and in August in Europe. Marked geographical differences in serotype distribution were noted. Salmonella Enteritidis was especially dominant in Europe, but was much less common in Africa, Asia and America, where the variety of circulating serotypes was greater. Overall, the two data sets provided important information on travel risks which are also likely to apply to travellers from other western countries.

摘要

瑞典法定传染病数据库用于识别1997 - 2003年期间24803例与旅行相关的非伤寒沙门氏菌病病例。其中24358例(98.2%)有血清型数据,将这些数据与同期16255名有近期瑞典境外过夜旅行史的随机选择的瑞典居民的数据集进行比较。从东非返回的旅行者(471/100000旅行者;95%可信区间294 - 755)或印度次大陆返回的旅行者(474/100000;95%可信区间330 - 681)疾病风险最高。0 - 6岁儿童比其他年龄段旅行者风险更高(比值比2.4;95%可信区间2.1 - 2.8)。可以区分出一些明显的季节性模式,东亚12月(调整后)风险最高,欧洲8月风险最高。血清型分布存在明显的地理差异。肠炎沙门氏菌在欧洲尤其占主导地位,但在非洲、亚洲和美洲则不太常见,这些地区流行的血清型种类更多。总体而言,这两个数据集提供了关于旅行风险的重要信息,这些信息可能也适用于其他西方国家的旅行者。

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