Wejde Gisela, Montan Per, Lundström Mats, Stenevi Ulf, Thorburn William
Department of Ophthalmology, St Erik's Hospital, Stockholm, Sweden.
Acta Ophthalmol Scand. 2005 Feb;83(1):7-10. doi: 10.1111/j.1600-0420.2005.00377.x.
To investigate the epidemiology of postoperative endophthalmitis (POE) following cataract surgery in Sweden during a 3-year period, using the framework of the Swedish National Cataract Register.
Clinically presumed cases of POE were reported in a prospective survey involving all Swedish ophthalmic surgical units except one. Data on results of the intraocular culture and visual outcome after infection, as well as patient age and gender and various elements of the surgical procedure, were collected.
The nationwide incidence of POE was 0.0595%, representing 112 cases in 188 151 cataract operations. Gram-positive bacteria were the predominant aetiology, with an 84.6% share of culture-positive cases. A significantly decreased risk for POE was found for patients who had received prophylactic intracameral antibiotics (mainly cefuroxime) in comparison with those who had been treated with topical antibiotics only.
The prevalence of POE after cataract surgery in Sweden is at the lower end of the spectrum of incidence currently reported in the developed world. The administration of intracameral antibiotics may have contributed to these results.
利用瑞典国家白内障登记系统的框架，调查瑞典3年期间白内障手术后眼内炎（POE）的流行病学情况。
在一项前瞻性调查中报告临床疑似POE病例，该调查涉及除一家之外的所有瑞典眼科手术单位。收集眼内培养结果、感染后的视力预后数据，以及患者年龄、性别和手术过程的各种要素。
POE的全国发病率为0.0595%，在188151例白内障手术中有112例。革兰氏阳性菌是主要病因，在培养阳性病例中占84.6%。与仅接受局部抗生素治疗的患者相比，接受预防性前房内抗生素（主要是头孢呋辛）治疗的患者发生POE的风险显著降低。
瑞典白内障手术后POE的患病率处于目前发达国家报告的发病率范围的较低水平。前房内抗生素的使用可能促成了这些结果。
