[Quantitative determination of the epidermal G2-chalonelike factor in rat tissues by means of radial immunodiffusion].
作者信息
Okulov V B
出版信息
Biull Eksp Biol Med. 1979 Jul;88(7):114-6.
PMID:157177
Abstract
A high-molecular glycoprotein (epidermal G2 chalone) shown to be homogeneous by electrophoresis and immunochemistry was isolated from rat skin. It exerts a strong tissue-rather than species-specific antimitotic effect on the keratinizing epithelium. The paper is concerned with its quantitative immunodiffusion determination in some tissues by means of monospecific antiserum. A clear-cut correlation between the mitotic index and the epidermal G2 chalone level in the mucosa is shown with special reference to vaginal epithelium of rats during the estrual cycle.
摘要
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