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双同位素研究中的容积再现和双色标度:在免疫闪烁显像和骨定位中的应用

Volume rendering and bicolour scale in double isotope studies: application to immunoscintigraphy and bone landmarking.

作者信息

Loboguerrero A, Pérault C, Liehn J C

机构信息

Unité de Médecine Nucléaire et de Biophysique, Institut Jean Godinot, Reims, France.

出版信息

Eur J Nucl Med. 1992;19(3):201-4. doi: 10.1007/BF00173282.

DOI:10.1007/BF00173282
PMID:1572385
Abstract

Combining the volume rendering and bicolour visualization techniques is proposed as an aid in interpreting single photon emission tomography (SPET) immunoscintigraphy (IS) recorded simultaneously with SPET bone landmarking (BL). The combination helps in localizing abnormal monoclonal uptake and in differentiating it from a physiological radioactivity distribution. The so-called rendered images (RIs) are obtained in both IS and BL studies according to a depth- weighted maximum activity projection algorithm. Fused BL and IS RIs are constructed by a simple, pixel by pixel addition. They are displayed using a bicolour grey-red scale, which makes it possible to visualize both studies by a transparency effect. This method was applied to patients suspected of suffering colorectal or ovarian cancer recurrences, in whom monoclonal antibodies against carcinoembryonic antigen, B72-3 or OC125 labelled with indium-111 were used.

摘要

有人提出将容积再现和双色可视化技术结合起来,以辅助解读与单光子发射断层扫描(SPET)骨定位(BL)同时记录的单光子发射断层扫描(SPET)免疫闪烁成像(IS)。这种结合有助于定位异常的单克隆摄取,并将其与生理性放射性分布区分开来。根据深度加权最大活性投影算法,在IS和BL研究中均可获得所谓的再现图像(RI)。通过简单的逐像素相加构建融合的BL和IS RI。使用双色灰红标度显示它们,这使得通过透明度效应可视化两项研究成为可能。该方法应用于疑似结直肠癌或卵巢癌复发的患者,这些患者使用了用铟-111标记的抗癌胚抗原、B72-3或OC125的单克隆抗体。

相似文献

1
Volume rendering and bicolour scale in double isotope studies: application to immunoscintigraphy and bone landmarking.双同位素研究中的容积再现和双色标度:在免疫闪烁显像和骨定位中的应用
Eur J Nucl Med. 1992;19(3):201-4. doi: 10.1007/BF00173282.
2
Superimposition of computed tomography and single photon emission tomography immunoscintigraphic images in the pelvis: validation in patients with colorectal or ovarian carcinoma recurrence.
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Planar, SPET and three-dimensional immunoscintigraphy of suspected recurrent colorectal cancer using 111In-B72.3 (Oncoscint CR-OV): effect of administered activity.使用¹¹¹铟标记的B72.3(Oncoscint CR-OV)对疑似复发性结直肠癌进行平面、单光子发射计算机断层扫描(SPET)和三维免疫闪烁扫描:给药剂量的影响
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Clinical experience with radiolabelled monoclonal antibodies in the detection of colorectal and ovarian carcinoma recurrence and review of the literature.放射性标记单克隆抗体在检测结直肠癌和卵巢癌复发中的临床经验及文献综述
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Superiority of SPET to planar imaging in the detection of colorectal carcinomas with 111In monoclonal antibodies.用铟-111单克隆抗体检测结直肠癌时,单光子发射计算机断层扫描(SPET)相对于平面成像的优越性。
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[Indium 111-labeled antibodies in the detection of colorectal carcinoma].[铟111标记抗体在结直肠癌检测中的应用]
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本文引用的文献

1
Transfer and combination of digital image data.数字图像数据的传输与合并。
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Volume rendering in three-dimensional display of SPECT images.单光子发射计算机断层扫描(SPECT)图像三维显示中的容积再现技术。
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Three-dimensional display in nuclear medicine and radiology.核医学与放射学中的三维显示
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