Ee H L, Tan S H
National Skin Centre, Singapore, Republic of Singapore.
Clin Exp Dermatol. 2005 Mar;30(2):131-3. doi: 10.1111/j.1365-2230.2004.01683.x.
Scleroderma is a systemic disease with a myriad of cutaneous manifestations. Pigmentary disturbances have been described in scleroderma. While diffuse generalized hyperpigmentation and localized hypopigmentation with perifollicular hyper-pigmentation are well recognized, a vascular induced hyperpigmentation has only been recently described. In this paper, we report another unrecognized pigmentary abnormality in a 48-year-old patient who presented with a reticulate hyper-pigmentation affecting the trunk, upper and lower limbs. To our knowledge, cutaneous hyperpigmented reticulate scleroderma has not been reported previously.
硬皮病是一种具有多种皮肤表现的全身性疾病。硬皮病中已有色素沉着紊乱的相关描述。虽然弥漫性全身性色素沉着过度以及伴有毛囊周围色素沉着过度的局限性色素减退已广为人知，但血管性色素沉着过度直到最近才被描述。在本文中，我们报告了一名48岁患者身上另一种未被认识到的色素沉着异常情况，该患者表现为躯干、上肢和下肢出现网状色素沉着过度。据我们所知，皮肤色素沉着过度性网状硬皮病此前尚未见报道。
