Sahoo Sunati, Recant Wendy M
Department of Pathology, University of Louisville Hospital, Louisville, Kentucky 40202, USA.
Breast J. 2005 Mar-Apr;11(2):140-2. doi: 10.1111/j.1075-122X.2005.21616.x.
Columnar cell alteration in the breast encompasses a spectrum of pathologic changes ranging from simple columnar cell change to more complex columnar cell hyperplasia with and without atypia to in situ carcinoma, often with a micropapillary architecture. For reasons that remain unclear, the columnar cell lesions are associated with tubular carcinomas and lobular carcinoma in situ. Therefore it is important to be familiar with the spectrum of changes and the associated lesions, especially in breast core biopsies for further management.
乳腺柱状细胞改变包括一系列病理变化，从单纯的柱状细胞改变到更复杂的伴或不伴非典型性的柱状细胞增生，再到原位癌，通常具有微乳头结构。由于尚不清楚的原因，柱状细胞病变与小管癌和小叶原位癌相关。因此，熟悉这些变化谱及相关病变很重要，尤其是在乳腺粗针活检中，以便进行进一步处理。
