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诱导轻度低温后健康志愿者的复温:一项健康志愿者研究。

Rewarming of healthy volunteers after induced mild hypothermia: a healthy volunteer study.

作者信息

Williams A B, Salmon A, Graham P, Galler D, Payton M J, Bradley M

机构信息

Middlemore Hospital, Department of Intensive Care Medicine, Private Bag 93311, Otahuhu, Auckland, New Zealand.

出版信息

Emerg Med J. 2005 Mar;22(3):182-4. doi: 10.1136/emj.2003.007963.

DOI:10.1136/emj.2003.007963
PMID:15735265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1726709/
Abstract

OBJECTIVES

The study compares the efficacy of two active and one passive warming interventions in healthy volunteers with induced mild hypothermia.

METHODS

Eight volunteers were studied in a random order crossover design. Each volunteer was studied during re-warming from a core temperature of 35 degrees C with each of: a radiant warmer (Fisher & Paykel); a forced air warmer (Augustine Medical), and a polyester filled blanket, to re-warm.

RESULTS

No significant differences in re-warming rates were observed between the three warming devices. It was found that the subject's endogenous heat production was the major contributor to the re-warming of these volunteers. Metabolic rates of over 350 W were seen during the study.

CONCLUSIONS

For patients with mild hypothermia and in whom shivering is not contraindicated our data would indicate that the rate of re-warming would be little different whether a blanket or one of the two active devices were used. In the field, this may provide the caregiver a useful choice.

摘要

目的

本研究比较两种主动升温干预措施和一种被动升温干预措施对诱导性轻度体温过低的健康志愿者的疗效。

方法

采用随机顺序交叉设计对8名志愿者进行研究。每名志愿者在从35摄氏度的核心体温复温过程中,分别使用以下设备进行复温:辐射保暖器(费雪派克公司);强制空气保暖器(奥古斯汀医疗公司),以及聚酯填充毯。

结果

三种升温设备之间的复温速率未观察到显著差异。研究发现,受试者的内源性产热是这些志愿者复温的主要因素。研究期间观察到代谢率超过350瓦。

结论

对于轻度体温过低且不禁忌颤抖的患者,我们的数据表明,使用毯子或两种主动设备之一进行复温的速率几乎没有差异。在现场,这可能为护理人员提供一个有用的选择。

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本文引用的文献

1
Hypothermia in elderly patients presenting to accident & emergency during the onset of winter.冬季发病期前往急诊的老年患者体温过低情况。
Scott Med J. 2002 Feb;47(1):10-1. doi: 10.1177/003693300204700105.
2
Negative pressure rewarming vs. forced air warming in hypothermic postanesthetic volunteers.体温过低的麻醉后志愿者采用负压复温与强制空气加温的比较。
Anesth Analg. 2001 Jan;92(1):261-6. doi: 10.1097/00000539-200101000-00052.
3
The trauma triad of death: hypothermia, acidosis, and coagulopathy.死亡三联征:体温过低、酸中毒和凝血功能障碍。
AACN Clin Issues. 1999 Feb;10(1):85-94.
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The convective afterdrop component during hypothermic exercise decreases with delayed exercise onset.低温运动期间的对流性体温后降成分会随着运动开始时间的延迟而降低。
Aviat Space Environ Med. 1998 Jan;69(1):17-22.
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Postoperative management of hypothermia of intra-operative origin--experience with a forced-air convective warming device.术中低温的术后管理——使用强制空气对流加温装置的经验
S Afr J Surg. 1997 Aug;35(3):134-8.
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Efficacy of forced-air and inhalation rewarming by using a human model for severe hypothermia.使用人体模型对严重低温进行强制空气复温和吸入复温的效果。
J Appl Physiol (1985). 1997 Nov;83(5):1635-40. doi: 10.1152/jappl.1997.83.5.1635.
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Inhibition of shivering increases core temperature afterdrop and attenuates rewarming in hypothermic humans.抑制寒颤会增加体温过低的人体的核心体温后降,并减弱复温过程。
J Appl Physiol (1985). 1997 Nov;83(5):1630-4. doi: 10.1152/jappl.1997.83.5.1630.
8
Forced-air warming is no more effective than conventional methods for raising postoperative core temperature after cardiac surgery.对于心脏手术后提高术后核心体温,强制空气加温并不比传统方法更有效。
J Cardiothorac Vasc Anesth. 1997 Oct;11(6):708-11. doi: 10.1016/s1053-0770(97)90162-2.
9
Bair hugger forced-air warming maintains normothermia more effectively than thermo-lite insulation.百特强制空气升温系统比热轻保温毯更有效地维持体温正常。
J Clin Anesth. 1994 Jul-Aug;6(4):303-7. doi: 10.1016/0952-8180(94)90077-9.
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Treatment of mild immersion hypothermia by forced-air warming.通过强制空气加温治疗轻度低体温症。
Aviat Space Environ Med. 1994 Sep;65(9):803-8.