甲状腺许特尔（嗜酸性）细胞瘤：病因发病机制、诊断及临床意义
Hürthle (oncocytic) cell tumors of thyroid: etiopathogenesis, diagnosis and clinical significance.
作者信息
Sobrinho-Simões Manuel, Máximo Valdemar, Castro Inês Vieira de, Fonseca Elsa, Soares Paula, Garcia-Rostan Ginesa, Oliveira Manuel Cardoso de
机构信息
Department of Pathology, Medical Faculty of the University of Porto, Portugal.
出版信息
Int J Surg Pathol. 2005 Jan;13(1):29-35. doi: 10.1177/106689690501300104.
The etiopathogenesis and the classification of oncocytic (Hürthle cell) tumors of the thyroid is reviewed with an emphasis on the role played by mitochondrial and nuclear genetic abnormalities that interfere with mitochondrial function. Oxyphilia is classified into primary or secondary and the so-called Hürthle cell carcinoma is divided into oncocytic (Hürthle cell) variants of papillary and follicular carcinoma.
本文综述了甲状腺嗜酸细胞（许特莱细胞）肿瘤的病因发病机制及分类，重点阐述了干扰线粒体功能的线粒体和核基因异常所起的作用。嗜酸性分为原发性或继发性，所谓的许特莱细胞癌分为乳头状癌和滤泡状癌的嗜酸细胞（许特莱细胞）变体。
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