Mahony Timothy J, McCarthy Fiona M, Gravel Jennifer L, Corney Bruce, Young Peter L, Vilcek Stefan
Department of Primary Industries and Fisheries, Level 6 North, Queensland Biosciences Precinct, 306 Carmody Road, Brisbane, Qld 4072, Australia.
Vet Microbiol. 2005 Mar 20;106(1-2):1-6. doi: 10.1016/j.vetmic.2004.10.024. Epub 2005 Jan 26.
Eighty-nine bovine viral diarrhoea viruses (BVDV) from Australia have been genetically typed by sequencing of the 5' untranslated region (5'-UTR) and for selected isolates the N(pro) region of the viral genome. Phylogenetic reconstructions indicated that all of the samples examined clustered within the BVDV type 1 genotype. Of the 11 previously described genetic groups of BVDV-1, 87 of the samples examined in this study clustered with the BVDV-1c, while two samples clustered with the BVDV-1a. Based on these analyses there appears to be limited genetic variation within the Australian BVDV field isolates. In addition, the phylogenetic reconstructions indicate that the clustering of Australian BVDV in the phylogenetic trees is not a result of geographic isolation.
通过对5'非翻译区（5'-UTR）进行测序，并对选定的分离株的病毒基因组N(pro)区域进行测序，对来自澳大利亚的89种牛病毒性腹泻病毒（BVDV）进行了基因分型。系统发育重建表明，所有检测的样本都聚集在BVDV 1型基因型内。在先前描述的11个BVDV-1基因群中，本研究检测的样本中有87个与BVDV-1c聚集在一起，而两个样本与BVDV-1a聚集在一起。基于这些分析，澳大利亚BVDV田间分离株的遗传变异似乎有限。此外，系统发育重建表明，澳大利亚BVDV在系统发育树中的聚集不是地理隔离的结果。
