Hedinger C, von Hochstetter A R, Egloff B
Virchows Arch A Pathol Anat Histol. 1979 Jul 27;383(1):59-67. doi: 10.1007/BF00427010.
Testicular seminomas may occur in various forms, of which the classical and spermatocytic are distinct, the anaplastic or atypical seminomas, however, less clearly defined. Lately, a separate group of particular clinical significance, comprising seminomas with syncytiotrophoblastic giant cells (STGC), has been specified. Although this type of seminoma had been recognized morphologically long ago, recent investigations have shown its ability to secret HCG, a fact that raises serious difficulties in its differential diagnosis with combined seminomas and choriocarcinomas. Two cases of seminomas with STGC are presented and pertinent clinical and morphologic problems discussed.
睾丸精原细胞瘤可能以多种形式出现，其中经典型和精母细胞型截然不同，而间变性或非典型精原细胞瘤的定义则不太明确。最近，已明确了一组具有特殊临床意义的独立类型，包括伴有合体滋养层巨细胞（STGC）的精原细胞瘤。尽管这种类型的精原细胞瘤早在形态学上就已被认识，但最近的研究表明它能够分泌人绒毛膜促性腺激素（HCG），这一事实在其与混合型精原细胞瘤和绒毛膜癌的鉴别诊断中引发了严重困难。本文报告了2例伴有STGC的精原细胞瘤病例，并讨论了相关的临床和形态学问题。
