Morgan D A, Caillaud J M, Bellet D, Eschwege F
Clin Radiol. 1982 Mar;33(2):149-53. doi: 10.1016/s0009-9260(82)80044-5.
Gonadotrophin-producing seminomas can be identified in two ways: detection of human chorionic gonadotrophin (HCG) in the serum or urine, or histological identification of syncytiotrophoblastic giant cells, which can be shown to contain HCG by means of indirect immunoperoxidase techniques. A review of the histories of 14 patients with such tumours shows that they are associated with a worse prognosis than that of 'typical' seminomas, and tend to present with a more advanced stage of disease. These tumours are thus distinct, clinically and biologically, from typical seminomas, and their treatment needs to be planned accordingly.
检测血清或尿液中的人绒毛膜促性腺激素（HCG），或通过组织学鉴定合体滋养层巨细胞，借助间接免疫过氧化物酶技术可显示其含有HCG。对14例此类肿瘤患者病史的回顾表明，与“典型”精原细胞瘤相比，它们的预后更差，且往往呈现疾病的更晚期阶段。因此，这些肿瘤在临床和生物学上与典型精原细胞瘤不同，其治疗需要相应地进行规划。
