Hendriks Erik J M, Scholten-Peeters Gwendolijne G M, van der Windt Daniëlle A W M, Neeleman-van der Steen Catharina W M, Oostendorp Rob A B, Verhagen Arianne P
Department of Epidemiology, Maastricht University, Maastricht, The Netherlands Department of Research and Development, Dutch Institute of Allied Health Care, Amersfoort, The Netherlands Department of General Practice, Institute for Research in Extramural Medicine, Vrije Universiteit Medical Centre, Amsterdam, The Netherlands Center for Quality of Care Research, University Medical Center, Catholic University of Nijmegen, Nijmegen, The Netherlands Department of General Practice, Erasmus Medical Centre, Rotterdam, The Netherlands.
Pain. 2005 Apr;114(3):408-416. doi: 10.1016/j.pain.2005.01.006.
The objective of our prospective inception cohort study was to identify prognostic factors for poor recovery in patients with whiplash-associated disorders grade 1 or 2 who still had neck pain and accompanying complaints 2 weeks after the accident. The study was carried out in a primary health care setting in The Netherlands and included 125 patients. The primary outcome measure was functional recovery defined in terms of neck pain intensity or work disability without medication use. The secondary outcome measures included neck pain intensity, work disability and sick leave. The outcomes were assessed at 4, 12 and 52 weeks after the accident. Prognostic factors were identified by logistic regression analyses. One year after the injury, 64% of the patients were recovered. Factors related to poor recovery were female gender, a low level of education, high initial neck pain, more severe disability, higher levels of somatisation and sleep difficulties. Neck pain intensity and work disability proved to be the most consistent predictors for poor recovery. The accuracy of the predictions of the prognostic models was high, meaning that the models adequately distinguished patients with poor recovery from those regarded as recovered. These findings add to the growing body of evidence, indicating that socio-demographic, physical and psychological factors affect short- and long-term outcome after whiplash injury. Our findings also indicate that care providers can easily identify patients at risk for poor recovery with a visual analogue scale for initial pain intensity and work-related activities.
我们这项前瞻性起始队列研究的目的是,确定1级或2级挥鞭样损伤相关疾病患者在事故发生2周后仍有颈部疼痛及伴随症状时恢复不佳的预后因素。该研究在荷兰的一家初级卫生保健机构开展,纳入了125例患者。主要结局指标是根据颈部疼痛强度或无药物使用情况下的工作能力丧失来定义的功能恢复情况。次要结局指标包括颈部疼痛强度、工作能力丧失和病假情况。在事故发生后的4周、12周和52周对结局进行评估。通过逻辑回归分析确定预后因素。受伤一年后,64%的患者已康复。与恢复不佳相关的因素有女性性别、低教育水平、初始颈部疼痛程度高、残疾程度更严重、躯体化水平更高以及睡眠困难。颈部疼痛强度和工作能力丧失被证明是恢复不佳最一致的预测因素。预后模型预测的准确性很高,这意味着这些模型能够充分区分恢复不佳的患者和已康复的患者。这些发现增加了越来越多的证据,表明社会人口学、身体和心理因素会影响挥鞭样损伤后的短期和长期结局。我们的研究结果还表明,医疗服务提供者可以通过初始疼痛强度和与工作相关活动的视觉模拟量表轻松识别有恢复不佳风险的患者。