Kupce Eriks, Freeman Ray
Varian, Ltd, Eynsham, Oxford, UK.
J Magn Reson. 2005 Apr;173(2):317-21. doi: 10.1016/j.jmr.2004.12.004.
Multidimensional NMR spectroscopy can be speeded up by limited radial sampling of the time-domain evolution data. The resulting frequency-domain projections are used to reconstruct the full NMR spectrum. New algorithms are proposed to suppress back-projection artifacts while retaining optimum sensitivity. The method is illustrated by experiments on the 900 MHz HNCO spectrum of a protein, HasA.
多维核磁共振光谱可通过对时域演化数据进行有限的径向采样来加速。所得的频域投影用于重建完整的核磁共振谱。提出了新的算法来抑制反投影伪影,同时保持最佳灵敏度。通过对蛋白质HasA的900 MHz HNCO谱进行实验来说明该方法。