Wright Anthony D, Papendorf Olaf, König Gabriele M
Australian Institute of Marine Science, PMB No. 3, Townsville MC, Qld 4810, Australia.
J Nat Prod. 2005 Mar;68(3):459-61. doi: 10.1021/np049640w.
The new natural products 3,5-bis(2,4-dichlorophenoxy)-2,6-dichlorophenol (ambigol C, 1), a highly chlorinated aromatic compound, and 2,4-dichlorobenzoic acid (2) were isolated from the terrestrial cyanobacterium Fischerella ambigua together with the known compounds ambigol A (3) and tjipanazole D (4). All structures were secured by extensive spectroscopic analysis (1D and 2D NMR, MS, UV, IR). Ambigol C has moderate activity against Trypanosoma rhodesiense.
从陆生蓝藻费氏蓝藻中分离出了新的天然产物3,5-双(2,4-二氯苯氧基)-2,6-二氯苯酚(歧义醇C,1),一种高度氯化的芳香化合物,以及2,4-二氯苯甲酸(2),同时还分离出了已知化合物歧义醇A(3)和替帕那唑D(4)。所有结构均通过广泛的光谱分析(一维和二维核磁共振、质谱、紫外、红外)得以确定。歧义醇C对罗德西亚锥虫具有中等活性。