Fioole Bram, Kokke Marike, van Hillegersberg Richard, Rinkes Inne H Borel
Department of Surgery (G,04,228), University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands.
BMC Surg. 2005 Apr 1;5:7. doi: 10.1186/1471-2482-5-7.
The purpose of this study was to evaluate the long-term results of partial liver resection for benign liver lesions.
All patients operated on for benign liver lesions from 1991 to 2002 were included. Information was retrieved from medical records, the hospital registration system and by a telephonic questionnaire.
Twenty-eight patients with a median age of 41 years (17-71) were operated on (M/F ratio 5/23). The diagnosis was haemangioma in 8 patients, FNH in 6, HCA in 13 and angiomyolipoma in 1. Eight patients were known to have relevant co-morbidity. Median operating time was 207 minutes (45-360). The morbidity rate was 25% and no postoperative mortality was observed. Twenty-two patients (79%) had symptoms (mainly abdominal pain) prior to surgery. Twenty-five patients were reached for a questionnaire. The median follow up was 55 months (4-150). In 89% of patients preoperative symptoms had decreased or disappeared after surgery. Four patients developed late complications.
Long-term follow up after liver surgery for benign liver lesions shows considerable symptom relief and patient satisfaction. In addition to a correct indication these results justify major surgery with associated morbidity and mortality.
本研究的目的是评估良性肝病变部分肝切除的长期结果。
纳入1991年至2002年期间因良性肝病变接受手术的所有患者。通过病历、医院登记系统及电话调查问卷获取信息。
28例患者接受了手术，中位年龄41岁（17 - 71岁）（男/女比例为5/23）。诊断为血管瘤8例，局灶性结节性增生6例，肝细胞腺瘤13例，血管平滑肌脂肪瘤1例。已知8例患者有相关合并症。中位手术时间为207分钟（45 - 360分钟）。发病率为25%，未观察到术后死亡。22例患者（79%）术前有症状（主要为腹痛）。对25例患者进行了问卷调查。中位随访时间为55个月（4 - 150个月）。89%的患者术后术前症状减轻或消失。4例患者出现晚期并发症。
良性肝病变肝手术后的长期随访显示症状得到显著缓解，患者满意度较高。除了正确的手术指征外，这些结果证明了伴有发病率和死亡率的大手术的合理性。
