Mularoni Alessandro, Torreggiani Alberto, di Biase Arturo, Laffi Gian Luca, Tassinari Giorgio
Department of Ophthalmology, Maggiore Hospital, Bologna, Italy.
Ophthalmology. 2005 Apr;112(4):660-6. doi: 10.1016/j.ophtha.2004.10.050.
To evaluate the use of the intracorneal ring (ICR; Intacs, Addition Technology, Inc., Fremont, CA) for the treatment of pellucid marginal degeneration (PMD).
Case series.
Eight patients with PMD who were intolerant to contact lenses received ICR segments in the superior cornea (0.25 mm thickness) and in the inferior cornea (0.45 mm thickness). The diagnosis was supported by Orbscan II tomography (Bausch & Lomb).
Preoperative and postoperative uncorrected visual acuity, best spectacle-corrected visual acuity (BSCVA), refractive astigmatism, and spherical equivalent were assessed. Changes in corneal shape were evaluated by corneal tomographic maps.
The minimum follow-up was 12 months (range, 12-42 months; standard deviation [SD], 14.14). Uncorrected visual acuity improved in all 8 eyes (100%). At the last postoperative examination, 6 eyes (75%) had a BCVA > or =20/25; mean postoperative refractive astigmatism was -2.53 (range, -4.50 to -1.25; SD, 1.03). Mean postoperative spherical equivalent was -1.52 (range, -7.25 to +1.87; SD, 3.01). At the third postoperative month, refractive stability was obtained. No patients lost any Snellen lines of BCVA. No intraoperative and postoperative complications occurred.
Intracorneal ring implantation is a promising new treatment for patients with early to moderate PMD and who are intolerant of contact lenses.
评估角膜内环(ICR;Intacs,Addition Technology公司,弗里蒙特,加利福尼亚州)治疗透明边缘变性(PMD)的效果。
病例系列。
8例不耐受隐形眼镜的PMD患者接受了角膜上缘(0.25毫米厚)和角膜下缘(0.45毫米厚)的ICR植入。诊断由Orbscan II断层扫描(博士伦公司)支持。
评估术前和术后的裸眼视力、最佳矫正视力(BSCVA)、屈光性散光和球镜等效度。通过角膜断层图像评估角膜形状的变化。
最短随访时间为12个月(范围12 - 42个月;标准差[SD],14.14)。所有8只眼(100%)的裸眼视力均有改善。在术后最后一次检查时,6只眼(75%)的最佳矫正视力≥20/25;术后平均屈光性散光为-2.53(范围-4.50至-1.25;SD,1.03)。术后平均球镜等效度为-1.52(范围-7.25至+1.87;SD,3.01)。术后第三个月获得屈光稳定性。没有患者最佳矫正视力下降一行。未发生术中及术后并发症。
角膜内环植入术对于早期至中度PMD且不耐受隐形眼镜的患者是一种有前景的新治疗方法。