Harper Julie
Department of Dermatology, University of Alabama, Birmingham, USA.
Manag Care Interface. 2005 Mar;18(3):51-5.
Few pharmacoeconomic studies exist regarding the use of topical retinoids for inflammatory acne vulgaris. Those pharmacoeconomic studies that do exist predictably involve new entrants (topical tazarotene in various formulations). The use of topical retinoids in combination with antimicrobial agents constitutes cost-effective therapy for inflammatory acne. The growing U.S. trend toward use of isotretinoin for less-severe forms of acne instead of topical retinoid-based combination therapy is problematic from clinical and cost perspectives. More pharmacoeconomic studies that consider the importance of compliance are necessary for clinicians and managed care professionals to make informed choices about the treatment of inflammatory acne.
关于外用维甲酸治疗寻常性炎性痤疮的药物经济学研究很少。现有的那些药物经济学研究可以预见地涉及新进入市场的药物（各种剂型的外用他扎罗汀）。外用维甲酸与抗菌剂联合使用构成了治疗炎性痤疮的具有成本效益的疗法。从临床和成本角度来看，美国越来越倾向于使用异维A酸治疗不太严重的痤疮形式，而不是基于外用维甲酸的联合疗法，这是有问题的。临床医生和管理式医疗专业人员需要更多考虑依从性重要性的药物经济学研究，以便就炎性痤疮的治疗做出明智的选择。
