Christensen H Collatz, Schüz J, Kosteljanetz M, Poulsen H Skovgaard, Boice J D, McLaughlin J K, Johansen C
Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
Neurology. 2005 Apr 12;64(7):1189-95. doi: 10.1212/01.WNL.0000156351.72313.D3.
To evaluate a possible association of glioma or meningioma with use of cellular telephones, using a nationwide population-based case-control study of incident cases of meningioma and glioma.
The authors ascertained all incident cases of glioma and meningioma diagnosed in Denmark between September 1, 2000, and August 31, 2002. They enrolled 252 persons with glioma and 175 persons with meningioma aged 20 to 69. The authors also enrolled 822 randomly sampled, population-based controls matched for age and sex. Information was obtained from personal interviews, medical records containing diagnoses, and the results of radiologic examinations. For a small number of cases and controls, the authors obtained the numbers of incoming and outgoing calls. They evaluated the memory of the respondents with the Mini-Mental State Examination and obtained data on socioeconomic factors from Statistics Denmark.
There were no material socioeconomic differences between cases and controls or participants and non-participants. Use of cellular telephone was associated with a low risk for high-grade glioma (OR, 0.58; 95% CI, 0.37 to 0.90). The risk estimates were closer to unity for low-grade glioma (1.08; 0.58 to 2.00) and meningioma (1.00; 0.54 to 1.28).
The results do not support an association between use of cellular telephones and risk for glioma or meningioma.
通过一项基于全国人口的胶质瘤和脑膜瘤新发病例病例对照研究，评估胶质瘤或脑膜瘤与使用移动电话之间可能存在的关联。
作者确定了2000年9月1日至2002年8月31日期间在丹麦诊断出的所有胶质瘤和脑膜瘤新发病例。他们纳入了252例年龄在20至69岁之间的胶质瘤患者和175例脑膜瘤患者。作者还纳入了822名按年龄和性别匹配的随机抽样的、基于人群的对照。信息通过个人访谈、包含诊断的病历以及放射学检查结果获得。对于少数病例和对照，作者获取了来电和去电的数量。他们用简易精神状态检查表评估受访者的记忆力，并从丹麦统计局获取社会经济因素数据。
病例与对照之间或参与者与非参与者之间在社会经济方面没有实质性差异。使用移动电话与高级别胶质瘤的低风险相关（比值比，0.58；95%可信区间，0.37至0.90）。低级别胶质瘤（1.08；0.58至2.00）和脑膜瘤（1.00；0.54至1.28）的风险估计值更接近1。
结果不支持使用移动电话与患胶质瘤或脑膜瘤风险之间存在关联。
