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The role of hepatitis B virus integrations in the pathogenesis of human hepatocellular carcinoma.

作者信息

Bonilla Guerrero Ruben, Roberts Lewis R

机构信息

Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology and Mayo Clinic Cancer Center, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

出版信息

J Hepatol. 2005 May;42(5):760-77. doi: 10.1016/j.jhep.2005.02.005.

DOI:10.1016/j.jhep.2005.02.005
PMID:15826727
Abstract
摘要

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HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx.
小鼠中与乙肝病毒相关的肝癌发展依赖于信号转导及转录激活因子3（STAT3），并表明乙肝病毒X蛋白（HBx）具有致癌作用。
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