Wu Y, Nozaki T, Inamitsu T, Kubo C
Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Japan.
Eat Weight Disord. 2004 Dec;9(4):296-9. doi: 10.1007/BF03325085.
The aim of this study was to determine which physical and psychological factors influence the autonomic nervous system (ANS) of patients with anorexia nervosa (AN).
The subjects were 14 AN patients and 12 healthy controls. Beat to beat heart rate variability recorded in a supine position with a controlled respiratory rate of 15/min, was analyzed using power spectral analysis. Symptoms of anxiety and depression were assessed by State and Trait Anxiety Inventory and Zung's Self-rating Depression Scale respectively.
Anxiety had a significant negative correlation with the ANS of AN patients. The illness duration times body mass index (BMI), a measure of sustained extreme loss of weight, was also significantly associated with changes in the ANS of AN patients.
Although the ANS is influenced by various factors, sustained extreme loss of weight seems to be more influential factor in AN patients.
本研究旨在确定哪些生理和心理因素会影响神经性厌食症（AN）患者的自主神经系统（ANS）。
研究对象为14名AN患者和12名健康对照者。使用功率谱分析对在仰卧位、呼吸频率控制为每分钟15次的情况下记录的逐搏心率变异性进行分析。焦虑和抑郁症状分别通过状态-特质焦虑量表和zung氏自评抑郁量表进行评估。
焦虑与AN患者的ANS呈显著负相关。病程乘以体重指数（BMI），即持续极度体重减轻的一种衡量指标，也与AN患者ANS的变化显著相关。
虽然ANS受多种因素影响，但持续极度体重减轻似乎是AN患者中更具影响力的因素。
