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伴有错误的自我复制。一种多核苷酸复制模型。

Self-replication with errors. A model for polynucleotide replication.

作者信息

Swetina J, Schuster P

出版信息

Biophys Chem. 1982 Dec;16(4):329-45. doi: 10.1016/0301-4622(82)87037-3.

Abstract

A model for polynucleotide replication is presented and analyzed by means of perturbation theory. Two basic assumptions allow handling of sequences up to a chain length of v approximately 80 explicitly: point mutations are restricted to a two-digit model and individual sequences are subsumed into mutant classes. Perturbation theory is in excellent agreement with the exact results for long enough sequences (v greater than 20).

摘要

本文提出了一种多核苷酸复制模型,并借助微扰理论对其进行分析。两个基本假设使得能够明确处理链长v约为80的序列:点突变限于两位数模型,且单个序列被归入突变类。对于足够长的序列(v大于20),微扰理论与精确结果非常吻合。

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