Robertson Bronwyn R, O'Rourke Jani L, Neilan Brett A, Vandamme Peter, On Stephen L W, Fox James G, Lee Adrian
Ramaciotti Centre for Gene Function Analysis, The University of New South Wales, Sydney, NSW 2052, Australia.
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW 2052, Australia.
Int J Syst Evol Microbiol. 2005 May;55(Pt 3):1199-1204. doi: 10.1099/ijs.0.63472-0.
The mammalian gastrointestinal tract is covered by a layer of mucus that can harbour a range of bacterial species specifically adapted to colonize this ecological niche. Examination of 110 bacterial isolates cultivated from the gastrointestinal tract of 23 mice revealed the presence of a subgroup of 30 isolates that did not correspond genetically with genera commonly associated with this site, i.e. members of the epsilon-Proteobacteria such as Helicobacter and Campylobacter species. Instead this group of isolates was found to lie within the phylum Deferribacteres, a completely distinct lineage in the domain Bacteria. There was a high level of consensus in results obtained from the phenotypic and genotypic characterization of a number of the isolates, which showed they were distinct from other members of the Deferribacteres. As such, they are proposed to constitute a new genus and species, Mucispirillum schaedleri gen. nov., sp. nov. These organisms are anaerobic, Gram-negative, spiral-shaped rods with bipolar flagella. The type strain is HRI I17(T) (= ATCC BAA-1009(T) = ACM 5223(T)).
哺乳动物的胃肠道被一层黏液覆盖，这层黏液中栖息着一系列特别适应在这个生态位定殖的细菌物种。对从23只小鼠胃肠道培养的110株细菌分离株进行检测发现，有30株分离株组成的一个亚组在基因上与通常与该部位相关的属不相符，即ε-变形菌门的成员，如幽门螺杆菌和弯曲杆菌属物种。相反，发现这组分离株属于脱铁杆菌门，这是细菌域中一个完全不同的谱系。从一些分离株的表型和基因型特征获得的结果具有高度一致性，表明它们与脱铁杆菌门的其他成员不同。因此，提议将它们归为一个新的属和种，即斯氏黏液螺旋菌（Mucispirillum schaedleri），新属，新种。这些生物体是厌氧的、革兰氏阴性、具有双极鞭毛的螺旋形杆菌。模式菌株是HRI I17(T)（=ATCC BAA - 1009(T)=ACM 5223(T)）。
