Zhang Le-Le, He Yan, Sheng Feiya, Hu Ying-Fan, Song Yu, Li Wei, Chen Jiarong, Zhang Jinming, Zou Liang
School of Basic Medical Sciences, Chengdu University, Chengdu, China.
Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu, China.
Chin Med. 2021 Sep 16;16(1):89. doi: 10.1186/s13020-021-00498-z.
Fagopyrum dibotrys (F. dibotrys) (D.Don) H.Hara is a well-known edible herbal medicine in Asian countries. It has been widely used for the treatment of lung diseases, swelling, etc., and is also an important part of many Chinese medicine prescriptions. At present, more than 100 compounds have been isolated and identified from F. dibotrys, and these compounds can be primarily divided into flavonoids, phenols, terpenes, steroids, and fatty acids. Flavonoids and phenolic compounds are considered to be the main active ingredients of F. dibotrys. Previous pharmacological studies have shown that F. dibotrys possesses anti-inflammatory, anti-cancer, anti-oxidant, anti-bacterial, and anti-diabetic activities. Additional studies on functional genes have led to a better understanding of the metabolic pathways and regulatory factors related with the flavonoid active ingredients in F. dibotrys. In this paper, we systemically reviewed the research advances on the phytochemistry and pharmacology of F. dibotrys, as well as the functional genes related to the synthesis of active ingredients, aiming to promote the development and utilization of F. dibotrys.
金荞麦（Fagopyrum dibotrys (D.Don) H.Hara）是亚洲国家一种著名的可食用草药。它已被广泛用于治疗肺部疾病、肿胀等，也是许多中药方剂的重要组成部分。目前，已从金荞麦中分离鉴定出100多种化合物，这些化合物主要可分为黄酮类、酚类、萜类、甾体类和脂肪酸类。黄酮类和酚类化合物被认为是金荞麦的主要活性成分。以往的药理学研究表明，金荞麦具有抗炎、抗癌、抗氧化、抗菌和抗糖尿病活性。对功能基因的进一步研究有助于更好地理解与金荞麦黄酮活性成分相关的代谢途径和调控因子。本文系统综述了金荞麦的植物化学、药理学以及与活性成分合成相关的功能基因的研究进展，旨在促进金荞麦的开发利用。
