Trost Barry M, Stiles Dylan T
Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.
Org Lett. 2005 May 26;7(11):2117-20. doi: 10.1021/ol050395x.
[reaction: see text]. A variety of N-substituted allenes have been synthesized by the copper-catalyzed coupling reaction between allenyl halides and amides, carbamates, and ureas. The reactions proceed in good to excellent yield using 7 mol % copper thiophenecarboxylate and 15 mol % of a diamine catalyst.
[反应：见正文]。通过铜催化的卤代丙二烯与酰胺、氨基甲酸酯和脲之间的偶联反应，已合成了多种N-取代丙二烯。使用7摩尔%的噻吩羧酸铜和15摩尔%的二胺催化剂，反应以良好至优异的产率进行。
