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戒烟:肺癌治疗的重要组成部分。

Smoking cessation: an integral part of lung cancer treatment.

机构信息

Department of Physiological Nursing - Gerontology, University of California San Francisco, San Francisco, CA 94143-0610, USA.

出版信息

Oncology. 2010;78(5-6):289-301. doi: 10.1159/000319937. Epub 2010 Aug 11.

DOI:10.1159/000319937
PMID:20699622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2945268/
Abstract

UNLABELLED

Lung cancer is the leading cause of cancer death in the US. About 50% of lung cancer patients are current smokers at the time of diagnosis and up to 83% continue to smoke after diagnosis. A recent study suggests that people who continue to smoke after a diagnosis of early-stage lung cancer almost double their risk of dying. Despite a growing body of evidence that continued smoking by patients after a lung cancer diagnosis is linked with less effective treatment and a poorer prognosis, the belief prevails that treating tobacco dependence is useless. With improved cancer treatments and survival rates, smoking cessation among lung cancer patients has become increasingly important. There is a pressing need to clarify the role of smoking cessation in the care of lung cancer patients.

OBJECTIVE

This paper will report on the benefits of smoking cessation for lung cancer patients and the elements of smoking cessation treatment, with consideration of tailoring to the needs of lung cancer patients.

RESULTS

Given the significant benefits of smoking cessation and that tobacco dependence remains a challenge for many lung cancer patients, cancer care providers need to offer full support and intensive treatment with a smoking cessation program that is tailored to lung cancer patients' specific needs.

CONCLUSION

A tobacco dependence treatment plan for lung cancer patients is provided.

摘要

目的:本文将报告肺癌患者戒烟的益处,以及戒烟治疗的要素,同时考虑根据肺癌患者的需求进行调整。

结论:提供了针对肺癌患者的烟草依赖治疗计划。

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本文引用的文献

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Does smoking cessation improve health-related quality-of-life?戒烟是否能提高健康相关的生活质量?
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Smoking cessation is challenging even for patients recovering from lung cancer surgery with curative intent.即使是那些意图治愈的肺癌手术后的患者,戒烟也具有挑战性。
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7
Effect of change in symptoms, respiratory status, nutritional profile and quality of life on response to treatment for advanced non-small cell lung cancer.症状、呼吸状况、营养状况及生活质量的变化对晚期非小细胞肺癌治疗反应的影响
Asian Pac J Cancer Prev. 2008 Oct-Dec;9(4):557-62.
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Cost-effectiveness of a smoking cessation program implemented at the time of surgery for lung cancer.肺癌手术时实施的戒烟计划的成本效益。
J Thorac Oncol. 2009 Apr;4(4):499-504. doi: 10.1097/JTO.0b013e318195e23a.
9
Overcoming CYP1A1/1A2 mediated induction of metabolism by escalating erlotinib dose in current smokers.通过在当前吸烟者中递增厄洛替尼剂量克服CYP1A1/1A2介导的代谢诱导作用。
J Clin Oncol. 2009 Mar 10;27(8):1220-6. doi: 10.1200/JCO.2008.19.3995. Epub 2009 Jan 21.
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Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines.尼古丁可诱导多种人类癌细胞系发生细胞增殖、侵袭及上皮-间质转化。
Int J Cancer. 2009 Jan 1;124(1):36-45. doi: 10.1002/ijc.23894.