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发展中国家无症状男性和女性冠状动脉钙化的患病率:与美国数据的比较。

Prevalence of coronary artery calcium among asymptomatic men and women in a developing country: comparison with the USA data.

作者信息

Dakik Habib A, Skouri Hadi N, Mehio-Sibai Abla, Sibai Tarek, Alam Samir, Sawaya Jaber, Nasrallah Antoine, Wehbeh Chadi, Ayach Kamal, Abchee Antoine B

机构信息

Department of Internal Medicine, Faculty of Medicine, American University of Beirut-Medical Center, P.O. Box 11-0236, Beirut, Lebanon.

出版信息

Atherosclerosis. 2005 Nov;183(1):141-5. doi: 10.1016/j.atherosclerosis.2005.03.038.

Abstract

BACKGROUND

Coronary artery calcium score (CACS) correlates with atherosclerotic burden and predicts cardiac events. Most of the published data have been derived from the USA population.

OBJECTIVE

To study the prevalence of coronary calcium in an asymptomatic population from the eastern Mediterranean region and compare it to data obtained from a large population study in the USA.

RESULTS

A total of 1154 asymptomatic men and women from Lebanon underwent EBCT screening because of the presence of one or more CAD risk factors. Mean CACS as well as the percentile cut-points increased consistently with increasing age and, except for those above 74 years of age, were higher in men than women in each age stratum. Age, hypercholesterolemia, diabetes and smoking showed significant associations with CACS in men, while only age and hypercholesterolemia were significantly associated with CACS in women. Among men, the 75th and 90th percentile distributions were comparable to what is observed in developed countries such as the USA.

CONCLUSION

Findings, from this first study in the region, suggest that despite a higher rate of diabetes and smokers in our study population, the CACS distribution in Lebanon is similar to that observed in the USA.

摘要

背景

冠状动脉钙化积分(CACS)与动脉粥样硬化负荷相关,并可预测心脏事件。大多数已发表的数据来自美国人群。

目的

研究地中海东部地区无症状人群的冠状动脉钙化患病率,并将其与美国一项大型人群研究的数据进行比较。

结果

由于存在一个或多个CAD危险因素,共有1154名来自黎巴嫩的无症状男性和女性接受了电子束CT筛查。平均CACS以及百分位数切点随年龄增长而持续增加,除74岁以上人群外,各年龄层男性的CACS均高于女性。年龄、高胆固醇血症、糖尿病和吸烟在男性中与CACS显著相关,而在女性中只有年龄和高胆固醇血症与CACS显著相关。在男性中,第75和第90百分位数分布与在美国等发达国家观察到的情况相当。

结论

该地区的第一项研究结果表明,尽管我们的研究人群中糖尿病和吸烟者的比例较高,但黎巴嫩的CACS分布与美国观察到的情况相似。

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